Gene table of ECE1 : endothelin converting enzyme 1

Gene-disease associations table

Disease ID	Disease name	Source of annotation with ECE1	OMIM link	Number of associated genes	genes
613870	HIRSCHSPRUNG DISEASE, CARDIAC DEFECTS, AND AUTONOMIC DYSFUNCTION	OMIM, HUMSAVAR	link to OMIM	1	ECE1
145500	HYPERTENSION, ESSENTIAL	OMIM	link to OMIM	13	RGS5, PTGIS, ADD1, NOS3, UMOD, AGT, ECE1, CYP3A5, ATP1B1, NOS2, GNB3, AGTR1, SELE

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

Associated REACTOME pathways

Associated GO terms for Molecular function

GO term	GO ID	GO IC
peptide hormone binding	GO:0017046	6.13
hydrolase activity	GO:0016787	1.9
endopeptidase activity	GO:0004175	3.63
metalloendopeptidase activity	GO:0004222	5.02
cation binding	GO:0043169	1.4
amide binding	GO:0033218	4.14
ion binding	GO:0043167	1.36
catalytic activity	GO:0003824	1.05
metallopeptidase activity	GO:0008237	4.5
peptidase activity, acting on L-amino acid peptides	GO:0070011	3.26
protein dimerization activity	GO:0046983	2.72
binding	GO:0005488	0.18
protein binding	GO:0005515	0.46
peptide binding	GO:0042277	4.22
peptidase activity	GO:0008233	3.23
metal ion binding	GO:0046872	1.41
hormone binding	GO:0042562	5.53
identical protein binding	GO:0042802	2.63
protein homodimerization activity	GO:0042803	3.16